Name: Alexandre Casadesus
Position: PhD Student
Email: aclcri@ibmb.csic.es
Phone: +34 93 4020187
BioSketch
Alexandre graduated from the Universitat de Barcelona in 2020 with a degree in Biotechnology. During his studies, he completed an Erasmus exchange at the University of Helsinki, where he conducted his final bachelor’s thesis in neurobiology, investigating the role of arginine vasopressin in the brain during perinatal asphyxia. Following his undergraduate studies, he pursued a postgraduate degree in the Management of Research Projects for the Development of New Drugs at the Universitat de Barcelona. This program provided comprehensive training in all stages of drug development, from discovery and technology transfer to preclinical and final clinical phases. As part of an internship of this program, he joined the Mobile Clinical Services department at Labcorp (now Fortrea) as a Clinical Trial Assistant, managing multiple projects related to at-home clinical services for patients participating in diverse clinical trials, where he was hired full-time until September 2022. This experience deepened his interest in the early stages of drug development, leading him to pursue an MSc in Bioinformatics for Health Sciences at Universitat Pompeu Fabra (2022-2024). During his master’s studies, Alexandre deepened his knowledge in many fields within bioinformatics, spanning genomics, proteomics, structural bioinformatics, programming, data analysis and machine learning, among others. After completion of the first year, he engaged in several research internships focusing mainly in computational biology and structural bioinformatics. In July 2023, he joined the Structural Bioinformatics and Network Biology (SBNB) Lab at IRB Barcelona, where he worked on parsing relational databases for the construction of a future knowledge graph-related project. In November 2023, he transitioned to the Protein Design and Modeling Lab at IBMB, where he conducted his master’s thesis, focusing on the design of de novo proteins with immunoglobulin-like scaffolds. Upon completing his master’s, he remained at the lab as a researcher until the end of January 2025. In February 2025, Alexandre joined the Synthetic Structural Biology Lab at IBMB, working on the TransMisiones project in close collaboration with the Artificial Intelligence for Protein Design Lab (Noelia Ferruz) and the Systems and Synthetic Biology Lab (Marc Güell), both at CRG, as well as Integra Therapeutics. This ambitious project focuses on integrating deep learning-based protein design with advanced molecular technologies to develop next-generation virus-like particles (VLPs) for therapeutic applications.
