JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos
Abstract Morphogenesis of the Central Nervous System (CNS) is a complex process that obeys precise…
Structures of pMV158 replication initiator RepB with and without DNA reveal a flexible dual-function protein
A new hexameric and DNA-bound structure of RepB, the replication initiation protein of plasmid pMV158,…
A dynamic interplay between chitin synthase and the proteins Expansion/Rebuf reveals that chitin polymerisation and translocation are uncoupled in Drosophila
In this work we are advancing in our current understanding of the cellular and molecular…
Structure-function characterization of a virulence array of periodontopathogenic Tannerella forsythia
Periodontopathogenic Tannerella forsythia possesses the unique, tightly-regulated KLIKK-peptidase/potempin system in which six distinct metallo- and…
Expansion microscopy of the chick embryo neural tube to overcome molecular crowding at the centrosomes-cilia
Abstract We describe an optimized protocol for application of expansion microscopy (ExM) on chick neural…
Enrique Marcos, Murielle Saade and Esteban Hoijman promoted to Científicos Titulares
We are delighted to announce that Dr. Enrique Marcos and Dr. Murielle Saade, two Ramon…
Condensin pinches a short negatively supercoiled DNA loop during each round of ATP usage
SMCs are essential protein complexes highly conserved in all life kingdoms. SMCs fold chromosomal DNA…
Measuring ventral nerve cord stiffness in live flat-dissected Drosophila embryos by atomic force microscopy
Abstract Drosophila is an amenable system for addressing the mechanics of morphogen-esis. We describe a…
Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A‐related intellectual disability syndrome
DYRK1A haploinsufficiency alters the production of cortical astrocytes and oligodendrocyte progenitors during development, as well…
Choosing the right partner in hormone-dependent gene regulation: Glucocorticoid and progesterone receptors crosstalk in breast cancer cells
In this review, we summarized the state of the art of the functional cross-talk between…
Welcome Héctor García-Seisdedos
IBMB is excited to welcome Héctor García-Seisdedos to the Department of Structural Systems Biology!
Spatial genome organization, TGFβ, and biomolecular condensates: Do they talk during development?
In this review, we discuss how developmental signaling, epigenetics, and biochemical properties are coordinated to…