Molecular characterization of the histone demethylase PHF2 in maintaining proliferation, homeostasis and genomic integrity of neural progenitors
Thesis presented on Tuesday, 10th of September by Samuel Aguirre Infantes, at the Aula de…
Transcriptomic balance and optimal growth are determined by cell size
Whereas most cells maintain their size within limits, the underlying reasons are uncertain. Comparing cells…
Albert Carbonell, Marc Liesa and Naiara Akizu are joining the CHARLIE project
Dr. Albert Carbonell (Representative of the Scientific Committee of the Spanish association FamiliasGA and Research…
Point mutations at specific sites of the nsp12-nsp8 interface dramatically affect the RNA polymerization activity of SARS CoV-2
Viruses that have RNA as a genome exhibit a high degree of variability that allows…
PHF2-mediated H3K9me balance orchestrates heterochromatin stability and neural progenitor proliferation
The H3K9me2 demethylase PHF2 is essential for preserving heterochromatin stability and genome integrity in neural…
El IBMB tiene concedidas 5 ayudas de la convocatoria de Consolidación Investigadora 2023 por un importe total de 999.615,94 €
La Agencia Estatal de Investigación (AEI), organismo dependiente del Ministerio de Ciencia, Innovación y Universidades…
Nucleosomal DNA has topological memory
DNA molecules are precisely twisted and bent to shape the functional genome. The DNA Topology…
Research at the Chromatin Structure and Function Lab unveils the central contribution of somatic chromosome pairing to 3D genome organization
In collaboration with the Rowley’s lab at Nebraska University, researchers at the Chromatin Structure and…
KIS counteracts PTBP2 and regulates alternative exon usage in neurons
This study provides important new insights into the regulation of alternative splicing in neurons by…
Linker histone H1 regulates homeostasis of heterochromatin-associated cRNAs
cRNAs, a heterogeneous group of RNAs that copurify with chromatin, are abundant in heterochromatic transcripts…
Four IBMB members collaborate in the 18th Spanish Society for Developmental Biology Meeting
The Spanish Society for Developmental Biology (SEBD) is proud to announce the 18th meeting of…
New publication in eLife of the Jordan Lab in collaboration with the IBMB Imaging Platform showing that some human histone H1 variants are universally enriched at the nuclear periphery close to lamin while others are distributed throughout the nuclei, with the particularity of H1X being enriched within the nucleoli, with putative distinct participation on chromatin and nuclear structure organisation.
New publication in eLife of the Jordan Lab in collaboration with the IBMB Imaging Platform showing that…